FBI agents gather near the finish line of the Boston Marathon in Boston Tuesday, April 16, 2013. The bombs that ripped through the crowd at the Boston Marathon, killing at least three people and wounding more than 170, were fashioned out of pressure cookers and packed with shards of metal, nails and ball bearings to inflict maximum carnage, a person briefed on the investigation said Tuesday. (AP Photo/Winslow Townson)
FBI agents gather near the finish line of the Boston Marathon in Boston Tuesday, April 16, 2013. The bombs that ripped through the crowd at the Boston Marathon, killing at least three people and wounding more than 170, were fashioned out of pressure cookers and packed with shards of metal, nails and ball bearings to inflict maximum carnage, a person briefed on the investigation said Tuesday. (AP Photo/Winslow Townson)
Investigators in haz-mat suits examine the scene of the second bombing on Boylston Street in Boston Tuesday, April 16, 2013 near the finish line of the 2013 Boston Marathon, a day after two blasts killed at least three and injured over 170 people. (AP Photo/Elise Amendola)
In this Monday, April 15, 2013 photo, a race official assists Bill Iffrig, 78, of Lake Stevens, Wash., as Iffrig lies on the ground after the first explosion, as police officers react to a second explosion at the finish line of the Boston Marathon in Boston, Monday, April 15, 2013. Iffrig, of Lake Stevens, Wash., was running his third Boston Marathon and near the finish line when he was knocked down by one of two bomb blasts. (AP Photo/MetroWest Daily News, Ken McGagh) MANDATORY CREDIT
One of the blast sites on Boylston Street near the finish line of the 2013 Boston Marathon is seen in Boston, Tuesday, April 16, 2013, one day after bomb blasts killed three and injured over 140 people. FBI agents searched a suburban Boston apartment overnight and appealed to the public for amateur video and photos that might yield clues to who carried out the Boston Marathon bombing. (AP Photo/Elise Amendola)
In this Monday, April 15, 2013 photo, Boston Firefighter James Plourde carries an injured girl away from the scene after a bombing near the finish line of the Boston Marathon in Boston. The FBI's investigation into the bombings at the Boston Marathon was in full swing Tuesday, with authorities serving a warrant on a suburban Boston home and appealing for any private video, audio and still images of the blasts that killed at least three and wounded more than 170. (AP Photo/MetroWest Daily News, Ken McGagh) MANDATORY CREDIT
BOSTON (AP) ? Federal agents zeroed in Tuesday on how the Boston Marathon bombing was carried out ? with kitchen pressure cookers packed with explosives, nails and other lethal shrapnel ? but said they still didn't know who did it and why.
An intelligence bulletin issued to law enforcement and released late Tuesday included a picture of a mangled pressure cooker and a torn black bag the FBI said were part of a bomb.
The FBI and other law enforcement agencies repeatedly pleaded for members of the public to come forward with photos, videos or anything suspicious they might have seen or heard.
"The range of suspects and motives remains wide open," Richard DesLauriers, FBI agent in charge in Boston, said at a news conference. He vowed to "go to the ends of the Earth to identify the subject or subjects who are responsible for this despicable crime."
President Barack Obama branded the attack an act of terrorism but said officials don't know "whether it was planned and executed by a terrorist organization, foreign or domestic, or was the act of a malevolent individual."
Scores of victims remained in hospitals, many with grievous injuries, a day after the twin explosions near the marathon's finish line killed three people, wounded more than 170 and reawakened fears of terrorism. A 9-year-old girl and 10-year-old boy were among 17 victims listed in critical condition.
Heightening jitters in Washington, where security already had been tightened after the bombing, a letter addressed to a senator and poisoned with ricin or a similarly toxic substance was intercepted at a mail facility outside the capital, lawmakers said.
There was no immediate indication the episode was related to the Boston attack. Senate Majority Leader Harry Reid said the letter was sent to Republican Sen. Roger Wicker, of Mississippi.
Officials found that the bombs in Boston consisted of explosives put in ordinary 1.6-gallon pressure cookers, one with shards of metal and ball bearings, the other with nails, according to a person close to the investigation who spoke on condition of anonymity because the probe was still going on. The bombs were stuffed into black duffel bags and left on the ground, the person said.
DesLauriers confirmed that investigators had found pieces of black nylon from a bag or backpack and fragments of BBs and nails, possibly contained in a pressure cooker. He said the items were sent to the FBI laboratory at Quantico, Va., for analysis.
The FBI said it is looking at what Boston television station WHDH said are photos sent by a viewer that show the scene right before and after the bombs went off. The photo shows something next to a mailbox that appears to be a bag, but it's unclear what the significance is.
"We're taking a look at hundreds of photos, and that's one of them," FBI spokesman Jason Pack said.
Investigators said they haven't determined what was used to set off the explosives.
Pressure cooker explosives have been used in international terrorism and have been recommended for lone-wolf operatives by al-Qaida's branch in Yemen.
But information on how to make the bombs is readily found online, and U.S. officials said Americans should not rush to judgment in linking the attack to overseas terrorists.
DesLauriers said there had been no claim of responsibility for the attack.
He urged people to come forward with anything suspicious, such as hearing someone express an interest in explosives or a desire to attack the marathon, seeing someone carrying a dark heavy bag at the race or hearing mysterious explosions recently.
"Someone knows who did this," the FBI agent said.
The bombs exploded 10 or more seconds apart, tearing off victims' limbs and spattering streets with blood, instantly turning the festive race into a hellish scene of confusion, horror and heroics.
The blasts killed 8-year-old Martin Richard, of Boston, 29-year-old Krystle Campbell, of Medford, and a third victim, identified only as a graduate student at Boston University.
Doctors who treated the wounded corroborated reports that the bombs were packed with shrapnel intended to cause mayhem.
"We've removed BBs, and we've removed nails from kids. One of the sickest things for me was just to see nails sticking out of a little girl's body," said Dr. David Mooney, director of the trauma center at Boston Children's Hospital.
At Massachusetts General Hospital, all four amputations performed there were above the knee, with no hope of saving more of the legs, said Dr. George Velmahos, chief of trauma surgery.
"It wasn't a hard decision to make," he said. "We just completed the ugly job that the bomb did."
Obama plans to visit Boston on Thursday to attend an interfaith service in honor of the victims. He has traveled four times to cities reeling from mass violence, most recently in December after the schoolhouse shooting in Newtown, Conn.
In the wake of the attack, security was stepped up around the White House and across the country. Police massed at federal buildings and transit centers in the nation's capital, critical response teams deployed in New York City and security officers with bomb-sniffing dogs spread through Chicago's Union Station.
Homeland Security Secretary Janet Napolitano said that the stepped-up security was a precaution and that there was no evidence the bombings were part of a wider plot.
Pressure cooker explosives have been used in Afghanistan, India, Nepal and Pakistan, according to a July 2010 intelligence report by the FBI and the Department of Homeland Security. One of the three devices used in the May 2010 Times Square attempted bombing was a pressure cooker, the report said.
"Placed carefully, such devices provide little or no indication of an impending attack," the report said.
The Pakistani Taliban, which claimed responsibility for the 2010 attempt in Times Square, has denied any part in the Boston Marathon attack.
Al-Qaida's branch in Yemen gave a detailed description of how to make a bomb using a pressure cooker in a 2010 issue of Inspire, its English-language online publication aimed at would-be terrorists acting alone.
In a chapter titled "Make a bomb in the kitchen of your mom," it says "the pressurized cooker is the most effective method" for making a simple bomb, and it provides directions.
The tightly sealed pot makes easier-to-obtain but weaker explosives faster and stronger, amplifying the blast and the carnage.
Naser Jason Abdo, a former U.S. soldier, was sentenced to life in prison last year after being convicted of planning to use a pair of bombs made from pressure cookers in an attack on a Texas restaurant frequented by soldiers from Fort Hood. He was found with the Inspire article.
Investigators in the Boston bombing also are combing surveillance tapes from businesses around the finish line and asking travelers at Logan Airport to share any photos or video that might help.
"This is probably one of the most photographed areas in the country yesterday," said Boston police Commissioner Edward Davis. He said two security sweeps of the marathon route had been conducted before the bombing.
Boston police and firefighter unions announced a $50,000 reward for information leading to arrests.
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Sullivan reported from Washington. Associated Press writers Steve LeBlanc, Bridget Murphy, Rodrique Ngowi and Meghan Barr in Boston; Julie Pace and Lara Jakes in Washington; Paisley Dodds in London; Lee Keath in Cairo; and Marilynn Marchione in Milwaukee contributed to this report along with investigative researcher Randy Herschaft in New York.
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